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Paulo Dybala and Claudio Marchisio will miss the Champions League tie against Bayern Munich

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Paulo Dybala and Claudio Marchisio are out. Mario Mandzukic is a question mark

Giuseppe Bellini/Getty Images

Juventus striker Paulo Dybala and the Italian midfielder Claudio Marchisio are out of Wednesday’s Champions League round of 16 second leg tie against Bayern Munich. Both players sustained injuries in training, the Italian club stated on Tuesday.

Dybala didn’t suffer a mayor injury, but medical checks showed  the 22-year-old Argentine has suffered a minor muscle problem that will keep him from featuring in the tie. Marchisio suffered a calf injury during training, which was later revealed to be a first grade soleus muscle injury and the prognosis is that the Italian will be out of action for three weeks.

To further add to Juventus' pile of worries, Mario Mandzukic is a still a question mark after limping out of their 1-0 win over Sassuolo on Friday. Alvaro Morata is likely to start if the Croatian international is indeed ruled out, but without Dybala the club might be missing two of their their top three strikers in a clash where they need at least a single goal in any scenario to ensure advancement.